871950-91-3Relevant academic research and scientific papers
Fructose-fused γ-butyrolactones and lactams, synthesis and biological evaluation as GABA receptor ligands
Araujo, Ana C.,Nicotra, Francesco,Costa, Barbara,Giagnoni, Gabriella,Cipolla, Laura
, p. 1840 - 1848 (2008/12/21)
We describe the synthesis of sugar-fused β-disubstituted γ-butyrolactones, γ-butyrolactams and a lipophilic β-disubstituted GABA analogue as potential GABA receptor ligands, where the pharmacophore is engineered into the carbohydrate scaffold in the form
