872-41-3 Usage
General Description
3,6-Dihydro-2H-1,2-oxazine hydrochloride, also known as oxazine hydrochloride or morpholine hydrochloride, is a chemical compound that is commonly used as a reagent in organic synthesis and as a pharmaceutical intermediate. It has a white crystalline appearance and is soluble in water. The compound is used in the production of various pharmaceuticals, as well as in the synthesis of dyes and other organic compounds. It is also used as a corrosion inhibitor and as a stabilizer in some industries. Additionally, 3,6-Dihydro-2H-1,2-oxazine hydrochloride is known for its use as a sedative in veterinary medicine. Overall, this chemical compound has a wide range of applications in various industries, making it a versatile and important chemical reagent.
Check Digit Verification of cas no
The CAS Registry Mumber 872-41-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,7 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 872-41:
(5*8)+(4*7)+(3*2)+(2*4)+(1*1)=83
83 % 10 = 3
So 872-41-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H7NO/c1-2-4-6-5-3-1/h1-2,5H,3-4H2
872-41-3Relevant articles and documents
The Application of 1,2-Oxazinanes as Chiral Cyclic Weinreb Amide-Type Auxiliaries Leading to a Three-Component, One-Pot Reaction
F?hrmann, Jan,Hermann, Ludmila,Hilt, Gerhard
, (2021/12/17)
1,2-Oxazines were synthesised via a copper-catalysed aerobic acyl nitroso Diels-Alder reaction from 1,4-disubstituted 1,3-dienes and N-Boc-hydroxylamine. From this, 1,2-oxazinanes were obtained in a novel follow-up reaction path. The stability of several 1,2-oxazines and 1,2-oxazinanes towards organometallic compounds was tested to rate their operability as cyclic chiral Weinreb amide auxiliaries. 3,6-Di-tertbutyl-1,2-oxazinane gave the best results and was introduced as a chiral Weinreb amide-type auxiliary to yield chiral α-substituted ketones in a diastereomeric ratio of up to 98:2. The removal of the auxiliary can be performed with BuLi to form unsymmetrical α-chiral ketones. Thereafter, the chiral auxiliary can be re-isolated and purified by sublimation under vacuum.
