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High Quality1-N-methyl-2-pyrrolidone good supplier in stock
Cas No: 872-50-4
No Data 1 Kilogram 35000 Metric Ton/Year Ganzhou Zhongneng Industrial Co.,Ltd. Contact Supplier
Cas No: 872-50-4
No Data 1 Kilogram 50000 Metric Ton/Year SHANGHAI HUIAN CHEMICAL CO.LTD Contact Supplier
Cas No: 872-50-4
No Data 1 Gram Metric Ton/Day Hangzhou Share Chemical Co., Ltd Contact Supplier
1-Methyl-2-pyrrolidinone CAS 872-50-4 NMP 872-50-4 IN Stock N-Methylpyrrolidone CAS 872-50-4
Cas No: 872-50-4
USD $ 3.5-5.0 / Kiloliter 5 Kiloliter 3000 Metric Ton/Month Chemwill Asia Co., Ltd. Contact Supplier
Cas No: 872-50-4
No Data 1 Kilogram 3000 Metric Ton/Year Hefei TNJ chemical industry co.,ltd Contact Supplier
Cas No: 872-50-4
USD $ 4.0-5.0 / Gram 1 Gram 5-10 Metric Ton/Month Hangzhou Weck Chemical Industry Co., Ltd. Contact Supplier
Supply high quality N-methyl-pyrrolidinone
Cas No: 872-50-4
No Data 1 Kilogram 20000 Metric Ton/Year Aecochem Corp. Contact Supplier
Cas No: 872-50-4
No Data 1 Metric Ton 300 Metric Ton/Month Zibo Kunran Enterprises Co. LTD Contact Supplier
Cas No: 872-50-4
No Data 200 Kilogram 20000 Metric Ton/Day QINGDAO ON-BILLION INDUSTRAIL CO.,LTD Contact Supplier
Cas No: 872-50-4
USD $ 52.0-52.0 / Kilogram 1 Kilogram 2000 Metric Ton/Year Jinan Finer Chemical Co., Ltd Contact Supplier

872-50-4 Usage

Chemical Properties

1-Methyl-2-pyrrolidinone (NMP) has a molecular formula of C5H9NO, and it is a colorless to light yellow transparent liquid with a slight ammonia odor. Its boiling point is 204℃, flash point is 91℃, chroma HaZen≤25, refractive index N20D 1.468-1.471, density is 1.032-1.035. It is miscible in water at any ratio, it is soluble in ethanol, acetone, esters, halogenated hydrocarbons, aromatic hydrocarbons and other organic solvents, and it can completely mix with practically all solvents. It is strongly hygroscopic, chemically stable, not corrosive towards carbon steel and aluminum, and slightly corrosive to copper. It has low adhesiveness, strong chemical and thermal stability, high polarity, and low volatility. This product is slightly toxic, and its permitted concentration limit in air is 100PPM.

Air & Water Reactions

Soluble in water.

Chemical Properties

colourless or light yellow liquid with an amine odour


ChEBI: A member of the class of pyrrolidine-2-ones that is pyrrolidin-2-one in which the hydrogen attached to the nitrogen is replaced by a methyl group.

Contact allergens

1-Methylpyrrolidone is an aprotic solvent with a wide range of applications: petrochemical processing, surface coating, dyes and pigments, industrial and domestic cleaning compounds, and agricultural and pharmaceutical formulations. It is mainly an irritant, but it can cause severe contact dermatitis due to prolonged contact.


  1. 1-Methyl-2-pyrrolidinone (NMP) is a polar aprotic solvent that has the advantages of low toxicity, high boiling point, outstanding solvency, strong selectivity and good stability. It is widely used in purification of aromatic hydrocarbon extraction, acetylene, olefins, and diolefins.
  2. It is used in industrial cleaning, and it serves as a solvent for production of pesticides, engineering plastics, coatings, synthetic fibers, and integrated circuits.
  3. It can also be used as an industrial cleanser, dispersant, dye, lubricant and antifreeze.
  4. 1-Methyl-2-pyrrolidinone is an excellent solvent, widely used in aromatics extraction, lubricating oil refining, acetylene enrichment, butadiene separation and synthesis gas desulfurization.
  5. It is used in gas desulfurization, lubricating oil refining, lubricating oil antifreeze, olefin extraction, and as a solvent for insoluble engineering plastics polymerization.
  6. It can be used in herbicide, to clean insulation materials, semiconductor industry precision instruments and circuit boards, to recycle PVC exhaust, as a detergent, dye supplement and dispersing agent.
  7. It is used in mediums for polymerization reactions such as engineering plastics and aramid fiber.
  8. 1-Methyl-2-pyrrolidinone is used as a polyvinylidene fluoride solvent and electrode auxiliary material for lithium ion batteries.
  9. high purity grade for ICP-MS detection.
  10. For peptide synthesis.

Health Hazard

Inhalation of hot vapors can irritate nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Repeated and prolonged skin contact produces a mild, transient irritation.

Purification Methods

Dry the pyrrolidone by removing water as the *benzene azeotrope. Fractionally distil at 10 torr through a 100-cm column packed with glass helices. [Adelman J Org Chem 29 1837 1964, McElvain & Vozza J Am Chem Soc 71 896 1949.] The hydrochloride has m 86-88o (from EtOH or Me2CO/EtOH) [Reppe et al. Justus Liebigs Ann Chem 596 1 1955]. [Beilstein 21 II 213, 21 III/IV 3145, 21/6 V 321.]


It is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.

Fire Hazard

Special Hazards of Combustion Products: Toxic oxides of nitrogen may be formed in fire.

General Description

A clear colorless liquid with a "fishlike" odor. Denser than water. Flash point 199°F. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion.

Reactivity Profile

This amine is a very mild chemical base. 1-Methyl-2-pyrrolidinone does tend to neutralize acids to form salts plus water. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

872-50-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1601703)  ResidualSolventClass2-N-Methylpyrrolidone  United States Pharmacopeia (USP) Reference Standard 872-50-4 1601703-3X1.2ML 4,662.45CNY Detail
USP (1437202)  Methylpyrrolidone  United States Pharmacopeia (USP) Reference Standard 872-50-4 1437202-2G 4,588.74CNY Detail
Sigma-Aldrich (PHR1352)  N-Methylpyrrolidone  pharmaceutical secondary standard; traceable to USP 872-50-4 PHR1352-2G 718.73CNY Detail
Sigma-Aldrich (M79603)  1-Methyl-2-pyrrolidinone  ReagentPlus®, 99% 872-50-4 M79603-18L-CS 8,903.70CNY Detail
Sigma-Aldrich (M79603)  1-Methyl-2-pyrrolidinone  ReagentPlus®, 99% 872-50-4 M79603-4X4L 8,535.15CNY Detail
Sigma-Aldrich (M79603)  1-Methyl-2-pyrrolidinone  ReagentPlus®, 99% 872-50-4 M79603-6X1L 5,054.40CNY Detail
Sigma-Aldrich (M79603)  1-Methyl-2-pyrrolidinone  ReagentPlus®, 99% 872-50-4 M79603-4L 2,585.70CNY Detail
Sigma-Aldrich (M79603)  1-Methyl-2-pyrrolidinone  ReagentPlus®, 99% 872-50-4 M79603-2.5L 1,832.22CNY Detail
Sigma-Aldrich (M79603)  1-Methyl-2-pyrrolidinone  ReagentPlus®, 99% 872-50-4 M79603-1L 1,063.53CNY Detail
Sigma-Aldrich (443778)  1-Methyl-2-pyrrolidinone  ACS reagent, ≥99.0% 872-50-4 443778-18L-CS 9,734.40CNY Detail
Sigma-Aldrich (443778)  1-Methyl-2-pyrrolidinone  ACS reagent, ≥99.0% 872-50-4 443778-2.5L 2,033.46CNY Detail
Sigma-Aldrich (443778)  1-Methyl-2-pyrrolidinone  ACS reagent, ≥99.0% 872-50-4 443778-1L 1,196.91CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name N-methylpyrrolidin-2-one

1.2 Other means of identification

Product number -
Other names N-methyl-pyrrolidin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Adhesives and sealant chemicals,Intermediates,Paint additives and coating additives not described by other categories,Plating agents and surface treating agents,Processing aids, not otherwise listed,Processing aids, specific to petroleum production,Solvents (for cleaning or degreasing),Solvents (which become part of product formulation or mixture)
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:872-50-4 SDS

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