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872001-43-9

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872001-43-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 872001-43-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,2,0,0 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 872001-43:
(8*8)+(7*7)+(6*2)+(5*0)+(4*0)+(3*1)+(2*4)+(1*3)=139
139 % 10 = 9
So 872001-43-9 is a valid CAS Registry Number.

872001-43-9Upstream product

872001-43-9Downstream Products

872001-43-9Relevant academic research and scientific papers

Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists

Rotstein, David M.,Melville, Chris R.,Padilla, Fernando,Cournoyer, Dick,Lee, Eun K.,Lemoine, Remy,Petersen, Ann C.,Setti, Lina Q.,Wanner, Jutta,Chen, Lijing,Filonova, Lubov,Loughhead, David G.,Manka, Jason,Lin, Xiao-Fa,Gleason, Shelley,Sankuratri, Surya,Ji, Changhua,deRosier, Andre,Dioszegi, Marianna,Heilek, Gabrielle,Jekle, Andreas,Berry, Pamela,Mau, Cheng-I,Weller, Paul

scheme or table, p. 3116 - 3119 (2010/10/02)

Starting with a high-throughput screening lead, a novel series of CCR5 antagonists was developed utilizing an information-based approach. Improvement of pharmacokinetic properties for the series was pursued by SAR exploration of the lead template. The synthesis, SAR and biological profiles of the series are described.

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