872036-41-4 Usage
General Description
(S)-(-)-4-chloro-2-(1-hydroxyethyl)pyridine is a chemical compound with the molecular formula C7H8ClNO. It is a chiral compound, meaning it has two enantiomers - (S)-(-) and (R)-(+). (S)-(-)-4-chloro-2-(1-hydroxyethyl)pyridine is important in organic synthesis and pharmaceutical research, as it serves as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The hydroxyethyl group in the molecule makes it useful for the preparation of chiral ligands and catalysts, and it also has potential applications in the development of new drug molecules. Additionally, the chloro group in the compound makes it a versatile building block for the synthesis of diverse functionalized pyridine derivatives. Overall, (S)-(-)-4-chloro-2-(1-hydroxyethyl)pyridine is a valuable compound in organic chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 872036-41-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,2,0,3 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 872036-41:
(8*8)+(7*7)+(6*2)+(5*0)+(4*3)+(3*6)+(2*4)+(1*1)=164
164 % 10 = 4
So 872036-41-4 is a valid CAS Registry Number.
872036-41-4Relevant articles and documents
Biocatalytic preparation of optically active 4-(N,N-dimethylamino)pyridines for application in chemical asymmetric catalysis
Busto, Eduardo,Gotor-Fernandez, Vicente,Gotor, Vicente
, p. 1007 - 1016 (2006)
4-Chloro-2-(1-hydroxybenzyl)pyridine and 4-chloro-2-(1-hydroxyalkyl)pyridines were obtained with moderate to excellent enantiomeric excesses and high isolated yields by bioreduction with Baker's yeast of the corresponding ketones. The resulting optically active alcohols were transformed into adequate DMAP derivatives, which have been applied in asymmetric catalytic processes as nucleophilic catalysts in the stereoselective chemical alkoxycarbonylation of 1-phenylethanol or as chiral ligands in the enantioselective addition of diethylzinc to benzaldehyde.
