872056-38-7Relevant academic research and scientific papers
Paracyclophane-based carbene-copper catalyst tuned by transannular electronic effects for asymmetric boration
Chen, Jianqiang,Duan, Wenzeng,Chen, Zhen,Ma, Manyuan,Song, Chun,Ma, Yudao
, p. 75144 - 75151 (2016)
A series of planar chiral carbene-copper complexes based on the [2.2]paracyclophane backbone with a pseudo-ortho substitution pattern have been synthesized and applied to asymmetric β-boration of α,β-unsaturated esters. As a result, transannular electronic effects of the substituent of the chiral catalyst have significant influence on the catalytic performance. A variety of chiral β-hydroxyl esters were obtained in excellent enantioselectivities (up to 97% ee) and yields (up to 99%).
A chiral 6-membered n -heterocyclic carbene copper(I) complex that induces high stereoselectivity
Park, Jin Kyoon,Lackey, Hershel H.,Rexford, Matthew D.,Kovnir, Kirill,Shatruk, Michael,McQuade, D. Tyler
supporting information; experimental part, p. 5008 - 5011 (2010/12/25)
A chiral 6-membered annulated N-heterocyclic (6-NHC) copper complex that catalyzes β-borylations with high yield and enantioselectivity was developed. The chiral 6-NHC copper complex is easy to prepare on the gram scale and is very active, showing 10000 turnovers at 0.01 mol % of catalyst without significant decrease of enantioselectivity and with useful reaction rates.
