87206-26-6

Upstream product

• 78963-50-5 (3R,4R)-4-acetoxy-3-<(1R)-(tert-butyldimethylsiloxy)ethyl>-1-(1-methoxycarbonyl-2-methylpropen-1-yl)-azetidin-2-one 
• 4457-32-3 4-nitrobenzyl chloroformate 

Downstream Products

• 80559-33-7 methyl 3-methyl-2-[(3S,4R)-4-{2-(p-nitrobenzyloxycarbonylmethyl)allyl}-3-{(1R)-1-(p-nitrobenzyloxycarbonyloxy)ethyl}-2-oxoazetidin-1-yl]-but-2-enoate 
• 97033-08-4 Acetic acid (2R,3R)-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-1-trimethylsilanyl-azetidin-2-yl ester 
• 80559-31-5 methyl 3-methyl-2-[(3S,4R)-3-[(1R)-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-2-oxo-4-allylazetidin-1-yl]but-2-enoate 

Relevant academic research and scientific papers

REACTION OF ACETOXYAZETIDINONES WITH TRIMETHYLSILYLACETYL THIOLESTERS: PREPARATION OF AZETIDINONE-THIOLESTER PRECURSORS TO CARBAPENEMS

Reaction of acetoxyazetidinones, 1 and 2, with trimethylsilylacetyl thiolesters 10 afforded azetidinone-thiolesters, 11 and 12, which are useful intermediates in the carbapenem synthesis.