872094-07-0Relevant academic research and scientific papers
One-pot synthesis of chiral dehydroproline esters: [3+2]-type cycloaddition reaction of allenylstannane and α-imino ester
Fuchibe, Kohei,Hatemata, Rina,Akiyama, Takahiko
, p. 11304 - 11310 (2006)
An enantioselective [3+2]-type cycloaddition of allenylstannane and α-imino ester was developed. Synthetic utility of the 4-stannyldehydroproline ester intermediate was demonstrated: iodine oxidation and Stille coupling reaction of the intermediate afforded optically active 4-iodo- and 4-aryldehydroproline esters in good yields and in high ees, respectively.
