87223-13-0Relevant academic research and scientific papers
Development and optimization of simple one-step methods for the synthesis of 4-amino-substituted 1,8-naphthalimides
Kindahl, Tomas,Chorell, Elin,Chorell, Erik
, p. 6175 - 6182 (2014)
The 1,8-naphthalimide central fragment can be found in a vast number of bioactive compounds and drugs in clinical trials, and can be recognized from their use as fluorescent probes. Of key importance for the fluorescent properties of the scaffold is the 4-amino substituent, which has also proven to be critical in several other chemical and biological applications. Because of the great interest in 1,8-naphthalimides in general, and 4-amino-substituted 1,8-naphthalimides in particular, we have developed and optimized one-step procedures with which to access these derivatives by using an experimental design approach. The multivariate studies of temperature, reaction time, and equivalents of substrates identified conditions with close to quantitative yields that could be applied to generate a range of 4-amino-substituted 1,8-naphthalimides in high yields.
COLORANTS, MASTERBATCH INCLUDING THE SAME, COLORING RESIN COMPOSITION, AND MOLDED ARTICLE
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Paragraph 0117-0118, (2021/10/15)
PROBLEM TO BE SOLVED: To provide a colorant which does not cause discoloration or fading even when exposed to high temperature conditions at the time of molding by virtue of having high heat resistance, does not cause color transfer to a mold and other resin parts by virtue of excellent bleeding resistance and excellent sublimation resistance, and does not impair the physical properties of the thermoplastic resin to be added. SOLUTION: There is provided a naphthalimide compound represented by the formula (1). (In the formula, R1 is H, or a substituted/unsubstituted amino group or a nitrogen-containing heterocyclic group; R2 is a halogen atom, an alkyl group, an alkoxy group, and a substituted/unsubstituted amino group; R3 is H, an amino group, an amide group, an alkoxy group, a carboxy group, a hydroxy group, a sulfo group, and a sulfonamide group; A is a linear or branched hydrocarbon group, a benzene ring, or a naphthalene ring; m is a number of 0 to 2, n is a number of 1 to 3.). SELECTED DRAWING: None COPYRIGHT: (C)2022,JPOandINPIT
Copper-catalyzed direct N-arylation of naphthalimides using diaryliodonium Salts
Mao, Song,Guo, Fenglou,Li, Juan,Geng, Xu,Yu, Jianjun,Han, Jianwei,Wang, Limin
supporting information, p. 1959 - 1962 (2013/09/24)
An effective copper-catalyzed N-arylation of naphthal-imides with diaryliodonium salts in toluene at 100 °C has been developed. This cross-coupling reaction gives the desired N-arylated 1,8-naphthalimides in moderate to good yields. The synthetic potentia
SYNTHESIS AND LUMINESCENCE PROPERTIES OF 4-SUBSTITUTED NAPHTHALENIC ANHYDRIDE AND NAPHTHALIMIDE
Krasovitskii, B. M.,Shevchenko, E. A.,Distanov, V. B.
, p. 1165 - 1168 (2007/10/02)
The reaction of 4-chlorophthalic anhydride with secondary amines yields a series of 4-substituted naphthalenic anhydrides which have strong luminescence in the yellow-green region. 4-Morpholinonaphthalic anhydride which has a high luminescence quantum yield was used to synthese N-substitutes imides of 4-morpholinonaphthenic acid which are more resistant to the action of alkali and are also yellow-green luminophores.The spectral and luminescence properties of these compounds were studied.
