872312-02-2

Upstream product

• 887476-50-8 (S)-2-[(5-Chloro-1-methoxymethoxy-1H-pyrrole-2-carbonyl)-amino]-3-((1R,2R)-2-nitro-cyclopropyl)-propionic acid 
• 827342-96-1 2-[(5-chloro-1-methoxymethoxy-1H-pyrrole-2-carbonyl)-amino]-3-(2-nitro-cyclopropyl)-propionic acid 9H-fluoren-9-ylmethyl ester 
• 1026352-71-5 Ile-OMOM 
• 802911-32-6 N-Z-isoleucine methoxymethyl ester 
• 321524-72-5 N-Z-3-(2S,3R)-β-methylphenylalanine 
• 802911-21-3 H-(βMe)Phe-Ile-OMOM 
• 802911-39-3 (S)-3-((1R,2R)-2-Nitro-cyclopropyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid 
• 802911-20-2 N-Fmoc-3-(2R,1'R,2'R)-(trans-2'-nitrocyclopropyl)alanine 
• 802911-19-9 Z-(β-Me)Phe-Ile-OMOM 
• 872311-67-6 (2S,3S)-2-{(2S,3R)-2-[(R)-2-Amino-3-((1R,2R)-2-nitro-cyclopropyl)-propionylamino]-3-phenyl-butyrylamino}-3-methyl-pentanoic acid methoxymethyl ester 
• 802911-27-9 (2S,4R)-((Z)-4-Propenyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-[(1R,2R)-2-carboxy-1-methyl-2-(4-methyl-benzyloxycarbonylamino)-ethyl] ester 
• 802911-25-7 (2S,4R)-((Z)-4-Propenyl)-pyrrolidine-1,2-dicarboxylic acid 2-[(1R,2R)-2-allyloxycarbonyl-1-methyl-2-(4-methyl-benzyloxycarbonylamino)-ethyl] ester 1-tert-butyl ester 
• 872311-81-4 (2S,3S)-2-{(2S,3R)-2-[(R)-2-((2S,3R)-2-Amino-3-phenyl-butyrylamino)-3-((1R,2R)-2-nitro-cyclopropyl)-propionylamino]-3-phenyl-butyrylamino}-3-methyl-pentanoic acid methoxymethyl ester 
• 802911-22-4 (2S,3S)-2-{(2S,3R)-2-[(R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-((1R,2R)-2-nitro-cyclopropyl)-propionylamino]-3-phenyl-butyrylamino}-3-methyl-pentanoic acid methoxymethyl ester 

Relevant academic research and scientific papers

Synthesis and precursor-directed biosynthesis of new hormaomycin analogues

Several new analogues of hormaomycin (1), a peptide lactone with interesting biological activities, were prepared by total synthesis or by precursor-directed biosynthesis. The new analogues 2a-c, 3a-c, O-MOM-1 and epi-O-MOM-1 as well as the model acyl tri

First total synthesis of hormaomycin, a naturally occurring depsipeptide with interesting biological activities

Some unique features were disclosed during the structure elucidation of the cyclic depsipeptide hormaomycin (1), first isolated in 1989 from a Streptomyces griseoflavus strain and found to have quite an interesting spectrum of biological activities. Besid