872333-41-0Relevant academic research and scientific papers
Studies towards a conjugate vaccine for anthrax: Synthesis of the tetrasaccharide side chain of the Bacillus anthracis exosporium
Adamo, Roberto,Saksena, Rina,Kovac, Pavol
, p. 1075 - 1089 (2007/10/03)
The first synthesis of β-L-glycoside 17 of the tetrasaccharide β-Ant-(1 → 3)-α-L-Rhap-(1 → 3)-α-L-Rhap-(1 → 2)-L-Rhap is described (Schemes 1-3). Its spacer can be functionalized to make it amenable to conjugation to proteins by different conjugation meth
Synthesis of the β anomer of the spacer-equipped tetrasaccharide side chain of the major glycoprotein of the Bacillus anthracis exosporium
Adamo, Roberto,Saksena, Rina,Kovac, Pavol
, p. 2579 - 2582 (2007/10/03)
The β glycoside of the tetrasaccharide sequence β-Ant-(1→3)- α-l-Rhap-(1→3)-α-l-Rhap-(1→2)-l-Rhap, whose aglycon allows conjugation to proteins, was synthesized for the first time. A stepwise synthetic approach was applied with thioglycosides as glycosyl
