872353-87-2Relevant academic research and scientific papers
NEW ANALOGS OF NITROBENZYLTHIOINOSINE
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Page/Page column 27-28, (2010/02/15)
This invention relates to new analogs or derivatives of nitrobenzylthioinosine, use of these new analogs of nitrobenzylthioinosine for the treatment of pain and various other diseases as well as pharmaceuticals comprising at least on new analog of nitrobe
Inhibition of nucleoside transport proteins by C8-alkylamine- substituted purines
Tromp, Reynier A.,Spanjersberg, Ronald F.,Von Frijtag Drabbe Künzel, Jacobien K.,IJzerman, Adriaan P.
, p. 321 - 329 (2007/10/03)
4-Nitrobenzylthioinosine (NBTI, 1) is a well-known inhibitor for the nucleoside transport protein ENT1. Here we report on the synthesis and the biological evaluation of compounds that are less polar than NBTI. Compound screening in our laboratory indicate
