872422-46-3Relevant academic research and scientific papers
Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity
Manetti, Fabrizio,Esté, José A.,Clotet-Codina, Imma,Armand-Ugón, Mercedes,Maga, Giovanni,Crespan, Emmanuele,Cancio, Reynel,Mugnaini, Claudia,Bernardini, Cesare,Togninelli, Andrea,Carmi, Caterina,Alongi, Maddalena,Petricci, Elena,Massa, Silvio,Corelli, Federico,Botta, Maurizio
, p. 8000 - 8008 (2007/10/03)
A simple and efficient methodology for the parallel solution-phase synthesis has been set up to obtain a series of thiouracils, in turn selectively S-benzylated under microwave irradiation to give new S-DABOs. Biological screening led to the identificatio
