872427-97-9Relevant academic research and scientific papers
The chalcogeno-Baylis-Hillman reaction: A new preparation of allylic alcohols from aldehydes and electron-deficient alkenes
Kataoka, Tadashi,Iwama, Tetsuo,Tsujiyama, Shin-Ichiro,Iwamura, Tatsunori,Watanabe, Shin-Ichi
, p. 11813 - 11824 (1998)
The chalcogeno-Baylis-Hillman reaction catalyzed by sulfides and selenides, the group 16 element compounds, in the presence of Lewis acids was developed. The reactions proceeded smoothly by the use of 1 equiv of TiCl4 to give the coupling products in moderate to good yields. Bischalcogenides and related compounds were investigated as a catalyst, and 1,5- diselenocyclooctane gave the best result owing to stabilization of a cationic intermediate by the transannular interaction.
Elongation of β-hydroxyenones by cross-metathesis
Silva, Franck A.,Gouverneur, Véronique
, p. 8705 - 8709 (2007/10/03)
Enantioenriched aldol products derived from enones are notoriously difficult to prepare due to their sensitivity to retro-aldolisation, elimination and the requirement of a large excess of the enone donor for their preparation. However, some success has b
