87247-18-5Relevant academic research and scientific papers
Enantioselective transfer hydrogenation of aliphatic ketones catalyzed by ruthenium complexes linked to the secondary face of β-cyclodextrin
Schlatter, Alain,Woggon, Wolf-D.
scheme or table, p. 995 - 1000 (2009/05/30)
Ruthenium-η-arene complexes attached to the secondary face of β-cyclodextrin catalyze the enantioselective reduction (ee up to 98%) of aliphatic and aromatic ketones in aqueous medium in the presence of sodium formate (HCOONa).
Asymmetric reduction of ketones by Geotrichum candidum in the presence of Amberlite Xad, A solid organic solvent
Nakamura, Kaoru,Fujii, Mikio,Ida, Yoshiteru
, p. 3205 - 3211 (2007/10/03)
Asymmetric reduction of ketones by Geotrichum candidum in the presence of Amberlite XAD, a solid organic solvent, was described. A hydrophobic polymer, XAD, was used as material to control the stereochemical course of microbial reductions. Aliphatic and aromatic ketones were reduced to the corresponding (S)-alcohols in excellent enantiomeric excess (ee) in the presence of XRD while low enantioselectivities were observed in the absence of the polymer.
