872516-08-0

Upstream product

• 138908-56-2 (S)-(+)-2-tert-butoxycarbonylamino-3-(3,4-dimethoxyphenyl)propionic acid methyl ester 
• 105779-71-3 (S)-(-)-[2-(3,4-dimethoxyphenyl)-1-hydroxymethylethyl]carbamic acid tert-butyl ester 
• 872516-04-6 (S)-(-)-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]carbamic acid tert-butyl ester 

Downstream Products

• 872516-20-6 (S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide 
• 872516-12-6 (S)-(-)-1-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]pyrrolidine-2,5-dione 

Relevant academic research and scientific papers

Diastereoselective intramolecular α-amidoalkylation reactions of L-DOPA derivatives. Asymmetric synthesis of pyrrolo[2,1-a]isoquinolines

Stereocontrolled intramolecular α-amidoalkylation reactions of L-DOPA-derived succinimides have been studied. Addition of MeLi to nonracemic succinimides 9a-d yields oxoamides, which are cyclized upon treatment with Lewis or protic acids to afford (5S,10b