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872577-01-0

4(5H)-Thiazolone, 2-[[2-(3-fluorophenyl)ethyl]amino]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 872577-01-0 Structure

  • Basic information

    1. Product Name: 4(5H)-Thiazolone, 2-[[2-(3-fluorophenyl)ethyl]amino]-
    2. Synonyms:
    3. CAS NO:872577-01-0
    4. Molecular Formula: C11H11FN2OS
    5. Molecular Weight: 238.286
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 872577-01-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4(5H)-Thiazolone, 2-[[2-(3-fluorophenyl)ethyl]amino]-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4(5H)-Thiazolone, 2-[[2-(3-fluorophenyl)ethyl]amino]-(872577-01-0)
    11. EPA Substance Registry System: 4(5H)-Thiazolone, 2-[[2-(3-fluorophenyl)ethyl]amino]-(872577-01-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 872577-01-0(Hazardous Substances Data)

872577-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 872577-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,2,5,7 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 872577-01:
(8*8)+(7*7)+(6*2)+(5*5)+(4*7)+(3*7)+(2*0)+(1*1)=200
200 % 10 = 0
So 872577-01-0 is a valid CAS Registry Number.

872577-01-0Downstream Products

872577-01-0Relevant articles and documents

Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors

Chen, Shaoqing,Chen, Li,Le, Nam T.,Zhao, Chunlin,Sidduri, Achyutharao,Lou, Jian Ping,Michoud, Christophe,Portland, Louis,Jackson, Nicole,Liu, Jin-Jun,Konzelmann, Fred,Chi, Feng,Tovar, Christian,Xiang, Qing,Chen, Yingsi,Wen, Yang,Vassilev, Lyubomir T.

, p. 2134 - 2138 (2008/02/03)

A novel series of quinolinyl-methylene-thiazolinones has been identified as potent and selective cyclin-dependent kinase 1 (CDK1) inhibitors. Their synthesis and structure activity relationships (SAR) are described. Representative compounds from this class reversibly inhibit CDK1 activity in vitro, and block cell cycle progression in human tumor cell lines, suggesting a potential use as antitumor agents.

Substituted 1,5-naphthyridine azolinones

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Page/Page column 15, (2010/11/24)

Substituted 1,5-naphthyridine azolinones inhibit Cdk1 and are selective against Cdk2 and Cdk4. These compounds and their pharmaceutically acceptable salts have antiproliferative activity and are useful as anti-cancer agents.

Quinazoline thiazolinones

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Page/Page column 11, (2008/06/13)

Quinazoline thiazolinone derivatives which demonstrate CDK1 antiproliferative activity and are useful as anti-cancer agents.

Thiazolinone 4-monosubstituted quinolines

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Page/Page column 35, (2010/10/20)

Thiazolinone monosubstituted quinoline derivatives where the quinoline ring is mono-substituted at the 4 positions which derivatives demonstrates CDK1 antiproliferative activity and are useful as anti-cancer agents.

Azaindole thiazolinones

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Page/Page column 16, (2010/10/20)

Azaindole thiazolinone derivatives which demonstrate CDK1 and CDK2 antiproliferative activities and are useful as anti-cancer agents.

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