872584-87-7Relevant academic research and scientific papers
Synthesis, Modification, and Antimicrobial Activity of the N-Methylpiperazinyl Amides of Triterpenic Acids
Kazakova,Giniyatullina,Tolstikov,Medvedeva,Utkina,Kartashova
experimental part, p. 383 - 389 (2011/05/06)
N-methylpyperazinyl amides of betulinic, platanic, glycyrrhetic, oleanolic, ursolic, and moronic acids were synthesized and modified. Betulin and betulonic acid showed antimicrobial activity against Staphylococcus aureus at a concentration of 90 mg/ml, and betulin manifested a bacteriostatic effect against Klebsiella pneumoniae at a concentration of 60 mg/ml. Among the studied N-methylpyperazinyl amides, the highest activity against S. aureus was observed for a betulonic acid derivative. Pleiades Publishing, Ltd., 2010.
Anti-retroviral moronic acid derivatives
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Page/Page column 6-7, (2008/06/13)
The present invention provides moronic acid derivatives of the general formula: which have antiviral activity, along with compositions containing the same and methods of use thereof.
