872619-06-2Relevant academic research and scientific papers
Stereoselectivity in metal carbene and Lewis acid-catalyzed reactions from diastereomeric dirhodium(II) carboxamidates: Menthyl N-acetyl-2- oxoimidazolidine-4(S)-carboxylates
Doyle, Michael P.,Morgan, John P.,Colyer, John T.
, p. 5525 - 5532 (2005)
The influence of a chiral menthyl group as the pendant ester substituent on the N-acetyl-2-oxoimidazolidine-4S-carboxylate ligands in chiral dirhodium(II) imidazolidinone catalysts has been examined. Significant match/mismatch influences are evident in the observed stereocontrol for carbon-hydrogen insertion reactions with diazoacetates, but these effects are minimal in cyclopropanation reactions. Steric restrictions prevent effective enantiocontrol in hetero-Diels-Alder reactions using these menthyl-substituted catalysts.
