872676-77-2Relevant academic research and scientific papers
Total synthesis as a resource in drug discovery: The first in vivo evaluation of panaxytriol and its derivatives
Yun, Heedong,Chou, Ting-Chao,Dong, Huajin,Tian, Yuan,Li, Yue-Ming,Danishefsky, Samuel J.
, p. 10375 - 10380 (2007/10/03)
We have conducted key preliminary studies into the in vitro and in vivo cytotoxicity of panaxytriol. Through total synthesis, we prepared and evaluated several synthetic panaxytriol analogues, each of which exhibited enhanced cytotoxicity relative to the
