87273-60-7Relevant articles and documents
STRUCTURE AND REACTIVITY OF 2-METHYL-9-HYDROXY-4H-PYRIDOPYRIMIDIN-4-ONE
Smirnov, L. D.,Nikitin, S. V.,Chernyshev, A. I.,Sorokin, A. A.,Lezina, V. P.,et al.
, p. 1425 - 1431 (1992)
It has been shown that the alkylation of 2-methyl-9-hydroxy-4H-pyridopyrimidin-4-one takes place at the oxygen atom, but electrophilic substitution takes place mainly at position 8 of the molecule (the ortho position relative to the hydroxy group).
NITROGEN BRIDGEHEAD COMPOUNDS PART 39. SYNTHESIS AND REACTIONS OF 3-PHENOXY-2-METHYL-4H-PYRIDOPYRIMIDIN-4-ONES
Balogh, Maria,Hermecz, Istvan,Szilagyi, Ildiko,Meszaros, Zoltan
, p. 1083 - 1088 (2007/10/02)
3-Phenoxy- and 3-chloro-2-methyl-4H-pyridopyrimidin-4-ones (2) and (5) were prepared by the reactions of 2-aminopyridines and 2-phenoxy- or 2-chloroacetatoacetate (4) and (7) in a mixture of phosphoryl chloride -- polyphosphoric acid.The ring-trans