87274-51-9Relevant academic research and scientific papers
AN ABNORMAL HYDROLYTIC C-N CLEAVAGE OF THE AMIDE GROUP IN N-SUBSTITUTED 4-CARBAMOYLTETRADECACHLOROTRIPHENYLMETHYL RADICALS, AND RELATED REACTIONS
Ballester, M.,Riera, J.,Castaner, J.,Onrubia, C.,Ubierna, J. J.
, p. 2121 - 2124 (2007/10/02)
The alkaline hydrolysis of amides p-(RCH2NHCO)-C6Cl4-C(C6Cl5)2 (R, CO2Et or CO2H) occurs via methylene-nitrogen bond cleavage.Under the given conditions, the amide group in the corresponding non-radical, triarylmethane species, and in 4-(benzylcarbamoyl)tetradecachlorotriphenylmethyl radical, does not undergo any hydrolysis.That abnormal cleavage is traced therefore to the radical character.
