872848-11-8Relevant academic research and scientific papers
SAR and mode of action of novel non-nucleoside inhibitors of hepatitis C NS5b RNA polymerase
Powers, Jay P.,Piper, Derek E.,Li, Yang,Mayorga, Veronica,Anzola, John,Chen, James M.,Jaen, Juan C.,Lee, Gary,Liu, Jinqian,Peterson, M. Greg,Tonn, George R.,Ye, Qiuping,Walker, Nigel P. C.,Wang, Zhulun
, p. 1034 - 1046 (2006)
Novel non-nucleoside inhibitors of the HCV RNA polymerase (NS5b) with sub-micromolar biochemical potency have been identified which are selective for the inhibition of HCV NS5b over other polymerases. The structures of the complexes formed between several
