872852-75-0Relevant academic research and scientific papers
Targeting FtsZ for antituberculosis drug discovery: Noncytotoxic taxanes as novel antituberculosis agents
Huang, Qing,Kirikae, Fumiko,Kirikae, Teruo,Pepe, Antonella,Amin, Amol,Respicio, Laurel,Slayden, Richard A.,Tonge, Peter J.,Ojima, Iwao
, p. 463 - 466 (2006)
Screening of 120 taxanes identified a number of compounds that exhibited significant antituberculosis activity. Rational optimization of selected compounds led to the discovery that the C-seco-taxane-multidrug-resistance (MDR) reversal agents (C-seco-TRAs
