872871-49-3Relevant academic research and scientific papers
Human sialidase inhibitors: Design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids
Magesh, Sadagopan,Savita, Vats,Moriya, Setsuko,Suzuki, Tohru,Miyagi, Taeko,Ishida, Hideharu,Kiso, Makoto
experimental part, p. 4595 - 4603 (2009/12/01)
Recent advances in the sialidase biology have clarified the role of human sialidases (NEU 1 to NEU4) in the development of various disease states such as cancer, diabetes and arteriosclerosis. Isoform selective human sialidase inhibitors could be a therap
Sulfonamide-based compounds as protein tyrosine kinase inhibitors
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Page/Page column 8/16; 8; 13, (2008/06/13)
Various sulfonamide-based compounds are able to selectively inhibit the Src family of tyrosine kinases. These compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.
