872882-96-7Relevant academic research and scientific papers
Pyridyl piperazines for the treatment of CNS disorders
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Page/Page column 14, (2010/02/15)
This invention is directed to compounds of Formula I and to pharmaceutical compositions comprising the compound of Formula I. where the dashed line represents an optional double bond; and where n is 1 or 2, and Ar1, Ar2, . . . and Z
PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN
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Page/Page column 42, (2010/11/24)
The present invention relates to novel pyridyl-lactams, compounds of the formula (I), wherein R1 is a group of the formula G1, G2, G3 or G4 depicted below, and R3, Y, R6, R7, R8, R13, a, n and m are as defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions, their preparation and intermediates therefrom, and their use in treating or preventing depression, anxiety, obsessive compulsive disorder (OCD) and other disorders for which a 5-HT1B antagonist is indicated.
