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872889-08-2

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872889-08-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 872889-08-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,2,8,8 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 872889-08:
(8*8)+(7*7)+(6*2)+(5*8)+(4*8)+(3*9)+(2*0)+(1*8)=232
232 % 10 = 2
So 872889-08-2 is a valid CAS Registry Number.

872889-08-2Downstream Products

872889-08-2Relevant academic research and scientific papers

Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain

Brumfield, Stephanie,Korakas, Peter,Silverman, Lisa S.,Tulshian, Deen,Matasi, Julius J.,Qiang, Li,Bennett, Chad E.,Burnett, Duane A.,Greenlee, William J.,Knutson, Chad E.,Wu, Wen-Lian,Sasikumar, T. K.,Domalski, Martin,Li, Cheng,Bertorelli, Rosalia,Grilli, Mariagrazia,Lozza, Gianluca,Reggiani, Angelo

, p. 7223 - 7226,4 (2012/12/12)

High throughput screening identified the pyridothienopyrimidinone 1 as a ligand for the metabotropic glutamate receptor 1 (mGluR1 = 10 nM). Compound 1 has an excellent in vivo profile; however, it displays unfavorable pharmacokinetic issues and metabolic

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