872988-58-4Relevant academic research and scientific papers
Prototropic isomerization of spiro[2,3]hexanes 1,1,5-trisubstituted with electron-acceptor groups into 1,3-disubstituted bicyclo[1.1.0]butanes
Razin,Ulin
, p. 189 - 193 (2007/10/03)
1,1-Dicyano- and 1,1-dialkoxycarbonylspiro[2.3]hexane-1-carbonitriles treated with lithium diisopropylamide or potassium tert-butylate in THF undergo a prototropic isomerization into 3-(2,2-dicyanoethyl)- and 3-(2,2- dialkoxycarbonylethyl)bicyclo[1.1.0]butane-1-carbonitriles respectively. 2005 Pleiades Publishing, Inc.
