873055-90-4

Usage

Uses

Used in Pharmaceutical Industry:
1,3-DIAMINE-4-TRIFLUOROMETHOXYBENZENE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of novel drug molecules. Its unique properties allow for the creation of compounds with specific therapeutic effects, enhancing the range of available treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 1,3-DIAMINE-4-TRIFLUOROMETHOXYBENZENE is utilized as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals. Its role in this industry is crucial for enhancing crop protection and yield.
Used in Organic Synthesis:
1,3-DIAMINE-4-TRIFLUOROMETHOXYBENZENE is employed as a building block in organic synthesis for constructing complex molecules. Its unique trifluoromethoxy group allows for the creation of a wide range of chemical structures, expanding the possibilities for chemical research and development.

Upstream product

• 2822-50-6 3-nitro-4-(trifluoromethoxy)aniline 
• 655-07-2 2,4-dinitro-1-(trifluoromethoxy)benzene 

Relevant academic research and scientific papers

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.