873056-50-9

Basic information

• Product Name: 2-(benzo[d][1,3]dioxol-5-yl)aniline
• Synonyms: 2-(benzo[d][1,3]dioxol-5-yl)aniline
• CAS NO: 873056-50-9
• Molecular Weight: 213.236
• Mol File: 873056-50-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-(benzo[d][1,3]dioxol-5-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzo[d][1,3]dioxol-5-yl)aniline(873056-50-9)
• EPA Substance Registry System: 2-(benzo[d][1,3]dioxol-5-yl)aniline(873056-50-9)

Safety Data

• Hazardous Substances Data: 873056-50-9(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 94839-07-3 3,4-(methylenedioxy)-benzeneboronic acid 
• 615-36-1 2-bromoaniline 

Downstream Products

• 1360593-35-6 C₂₀H₁₇NO₄S 
• 40141-86-4 [1,3]dioxolo[4,5-j]-6(5H)-phenanthridinone 
• 1426813-12-8 5-tosyl-[1,3]dioxolo[4,5-j]phenanthridin-6(5H)-one 

Relevant articles and documents

Metal-free tandem carbene N-H insertions and C-C bond cleavages

A metal-free C-H [5 + 1] annulation reaction of 2-arylanilines with diazo compounds has been achieved, giving rise to two types of prevalent phenanthridines via highly selective C-C cleavage. Compared to the simple N-H insertion manipulation of diazo, this method elegantly accomplishes a tandem N-H insertion/SEAr/C-C cleavage/aromatization reaction, and the synthetic utility of this new transformation is exemplified by the succinct syntheses of trisphaeridine and bicolorine alkaloids. This journal is

4CzIPN-tBu-Catalyzed Proton-Coupled Electron Transfer for Photosynthesis of Phosphorylated N-Heteroaromatics

2,4,5,6-Tetrakis(3,6-di-tert-butyl-9H-carbazol-9-yl)isophthalonitrile (4CzIPN-tBu) was developed as a photocatalyst for the phosphorus-radical-initiated cascade cyclization reaction of isocyanides. By using 4CzIPN-tBu as catalyst, we developed a visible-light-induced proton-coupled electron transfer strategy for the generation of phosphorus-centered radicals, via which a wide range of phosphorylated phenanthridines, quinolines, and benzothiazoles were successfully constructed.

Visible-Light-Driven Difluoromethylation of Isocyanides with S-(Difluoromethyl)diarylsulfonium Salt: Access to a Wide Variety of Difluoromethylated Phenanthridines and Isoquinolines

A highly efficient approach of visible-light-driven radical difluoromethylation of isocyanides to access a wide variety of difluoromethylated phenanthridines and isoquinolines is herein described. Electrophilic S-(difluoromethyl)diarylsulfonium salt proved to be a good difluoromethyl radical precursor under photoredox catalysis. A broad range of isocyanides were tolerated to furnish the corresponding difluoromethylated phenanthridines, isoquinolines, furo[3,2-c]pyridine, and pyrido[3,4-b]indole in moderate to excellent yields under mild conditions. A plausible mechanism was also proposed.