873308-13-5Relevant academic research and scientific papers
Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy
Guerrini, Gabriella,Costanzo, Annarella,Ciciani, Giovanna,Bruni, Fabrizio,Selleri, Silvia,Costagli, Camilla,Besnard, Francois,Costa, Barbara,Martini, Claudia,De Siena, Gaetano,Malmberg-Aiello, Petra
, p. 758 - 775 (2006)
The synthesis and the binding study of new 3-arylesters and 3-heteroarylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide 8-substituted are reported. The nature of these substituents (in terms of lipophilic and electronic features) seems to influence the bindin
