873336-77-7Relevant academic research and scientific papers
Hybrid-increased radical-scavenging activity of resveratrol derivatives by incorporating a chroman moiety of vitamin e
Yang, Jie,Liu, Guo-Yun,Lu, Dong-Liang,Dai, Fang,Qian, Yi-Ping,Jin, Xiao-Ling,Zhou, Bo
supporting information; experimental part, p. 12808 - 12813 (2011/02/22)
A winning combination: Resveratrol derivatives incorporating a chroman moiety of vitaminE were constructed, resulting in the remarkable enhancement in tris(2,4,6-trichloro-3,5-dinitrophenyl)methyl radical (HNTTM)-scavenging activity as compared with the parent molecules (see scheme). Reaction kinetic analysis, oxidative product identification, and redox potential determination demonstrate that the reaction is governed by a sequential proton-loss electron-transfer (SPLET) mechanism.
Chroman/catechol hybrids: Synthesis and evaluation of their activity against oxidative stress induced cellular damage
Koufaki, Maria,Theodorou, Elissavet,Galaris, Dimitrios,Nousis, Lambros,Katsanou, Efrosini S.,Alexis, Michael N.
, p. 300 - 306 (2007/10/03)
Three series of chromans substituted at positions 2 or 5 by catechol derivatives were synthesized, and their activity against oxidative stress induced cellular damage was studied. Specifically, the ability of the new molecules to protect cultured cells fr
