873424-63-6Relevant academic research and scientific papers
Gold(I)/Xiang-Phos-Catalyzed Asymmetric Intramolecular Cyclopropanation of Indenes and Trisubstituted Alkenes
Zhang, Pei-Chao,Wang, Yidong,Zhang, Zhan-Ming,Zhang, Junliang
, p. 7049 - 7052 (2018/11/24)
The first intramolecular enantioselective cyclopropanation of indenes and trisubstituted alkenes was accomplished by using new chiral phosphine X5 derived gold(I) complexes. This reaction is a straightforward, efficient method for constructing [5-3-6] fused-ring compounds with two vicinal all-carbon quaternary stereogenic centers, a core structure shared by numerous pharmacological products, and bioactive compounds. The salient features of this transformation include high enantioselectivity (up to >98% ee), excellent yield (>97%), and nice functional group tolerance.
Rhodium N-heterocyclic carbene-catalyzed [4 + 2] and [5 + 2] cycloaddition reactions
Lee, Sang Ick,Park, Se Yeoun,Park, Ji Hoon,Jung, Il Gu,Choi, Soo Young,Chung, Young Keun,Lee, Bun Yeoul
, p. 91 - 96 (2007/10/03)
A rhodium complex of N-heterocyclic carbene (NHC) has been developed for intra- and intermolecular [4 + 2] and intramolecular [5 + 2] cycloaddition reactions. This is the first use of a transition-metal NHC complex in a Diels-Alder-type reaction. For the
Au(I)-catalyzed cyclization of enynes bearing an olefinic cycle
Sang, Ick Lee,Soo, Min Kim,Mi, Ra Choi,Sun, Young Kim,Young, Keun Chung,Han, Won-Sik,Sang, Ook Kang
, p. 9366 - 9372 (2007/10/03)
(Chemical Equation Presented) Gold(I)-catalyzed cyclization of enynes containing an olefinic cycle has been studied. The introduction of an olefinic ring instead of a terminal alkene in enynes dramatically increased the yield of the reaction. Enynes havin
