873436-54-5Relevant academic research and scientific papers
Process for manufacturing of enantiomerically pure 3-hydroxy-3-phenyl-propylamin
-
Page/Page column 5, (2008/06/13)
The present invention relates to an improved process for preparing enantiomerically pure 3-hydroxy-3-phenyl-propylamines on an industrial scale using asymmetrical hydrogenation as a key step and optionally a special sequence of subsequent steps, using a catalyst system consisting of rhodium and chiral 4-(dicyclohexylphosphino)-2-(diphenyl-phosphino-methyl)-N-methyl-aminocarbonyl-pyrrolidine.
