87345-07-1Relevant academic research and scientific papers
CYCLOHEXANESPIROCOMPOUNDS FROM 1-AMINOCYCLOHEXENES AND PHENYLCARBAMOYLDIIMIDE
Forchiassin, M.,Russo, C.,Nardin, G.
, p. 2909 - 2912 (1983)
The unexpected behaviour of phenylcarbamoyldiimide towards 1-amino-cyclohexenes, leading to enamine derivates bearing a cyclohexanespirotriazolidinone substituent is reported.
REACTIVITY OF PHENYLCARBAMOYLDIIMIDE TOWARDS 1-AMINOCYCLOHEXENES
Forchiassin, Mirella,Russo, Claudio
, p. 243 - 248 (2007/10/02)
The reactivity of phenylcarbamoyldiimide towards 1-aminocyclohexenes depends on the amine moiety of these compounds: 1-pyrrolidinocyclohexenes furnish bicyclic 1,2,4-triazin-3-one derivatives 5, while 1-morpholino- and 1-piperidino-cyclohexenes lead to enamine derivatives 6 and 7 bearing a cyclohexanespirotriazolidinone system as a substituent.On acidic hydrolysis, compounds 5 give the corresponding hydroxy derivatives 10, while 6 and 7 lead to the imidazolone derivatives 17.
