873464-04-1Relevant articles and documents
Compounds and methods for inhibiting phosphate transport
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Page/Page column 32, (2016/05/02)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, A, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
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Page/Page column 45, (2012/02/01)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically ac
COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
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Page/Page column 61, (2012/02/01)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically ac
Fluorine-substituted dihydrobicyclomycins: Synthesis and biochemical and biological properties
Park, Boon-Saeng,Widger, William,Kohn, Harold
, p. 41 - 61 (2007/10/03)
Many studies show that selective introduction of fluorine within pharmacological agents leads to improved activities. In this study, we determine the effects of aryl fluorine substitution in 5a-(benzylsulfanyl)- dihydrobicyclomycin (3) on the in vitro inh