873465-46-4Relevant academic research and scientific papers
Development of urea and thiourea kynurenamine derivatives: Synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors
Chayah, Mariem,Carri?n, M. Dora,Gallo, Miguel A.,Jiménez, Rosario,Duarte, Juan,Camacho, M. Encarnaci?n
, p. 874 - 882 (2015/05/05)
Herein we describe the synthesis of a new family of kynurenamine derivatives with a urea or thiourea moiety, together with their in vitro biological evaluation as inhibitors of both neuronal and inducible nitric oxide synthases (nNOS and iNOS, respectivel
Kynurenamines as neural nitric oxide synthase inhibitors
Entrena, Antonio,Camacho, M. Encarnación,Carrión, M. Dora,López-Cara, Luisa C.,Velasco, Guillermo,Léon, Josefa,Escames, Germaine,Acu?a-Castroviejo, Dario,Tapias, Víctor,Gallo, Miguel A.,Vivó, Antonio,Espinosa, Antonio
, p. 8174 - 8181 (2007/10/03)
To find new compounds with potential neuroprotective activity, we have designed, synthesized, and characterized a series of neural nitric oxide synthase (nNOS) inhibitors with a kynurenamine structure. Among them, N-[3-(2-amino-5-methoxyphenyl)-3-oxopropy
