873576-79-5Relevant academic research and scientific papers
Design and synthesis of lipopeptide-carbohydrate assembled multivalent vaccine candidates using native chemical ligation
Zhong, Wei,Skwarczynski, Mariusz,Fujita, Yoshio,Simerska, Pavla,Good, Michael F.,Toth, Istvan
scheme or table, p. 993 - 999 (2010/03/02)
Development of a synthetic vaccine against group A streptococcal infection is increasingly paramount due to the induction of autoimmunity by the main virulent factor M protein. Peptide vaccines, however, are generally poorly immunogenic, necessitating adm
Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin
Hayes, Patricia Y.,Ross, Benjamin P.,Thomas, Bradley G.,Toth, Istvan
, p. 143 - 152 (2007/10/03)
Two polycationic lipophilic-core carbohydrate-based dendrons 2a-b and five polycationic lipophilic-core peptide dendrons 3-6, containing four arginine or lysine terminal residues, were synthesized and then tested in rats as penetration enhancers for the o
