873577-69-6Relevant articles and documents
Synthesis of spirolactams and spiropiperidines as CCR4 receptor antagonists
Hansen, Joshua D.,Newhouse, Bradley J.,Allen, Shelley,Anderson, Aaron,Eary, Todd,Schiro, Justin,Gaudino, John,Laird, Ellen,Allen, Andrew C.,Chantry, David,Eberhardt, Christine,Burgess, Laurence E.
, p. 69 - 72 (2007/10/03)
The synthesis of racemic and non-racemic spirocyclic lactams that display high binding affinity toward CCR4 is described. Two distinct series of spirocycles were prepared from the common intermediate 9.