87377-95-5

Upstream product

• 75-11-6 diiodomethane 
• 3376-35-0 Methylether von Acetonoxim 

Downstream Products

• 637-88-7 1,4-Cyclohexanedione 
• 87377-98-8 (E,E)-1,4-Cyclohexandion-bis 
• 87377-98-8 (Z,Z)-1,4-Cyclohexandion-bis 
• 87378-02-7 1-Phenyl-3,6-heptandion-bis 
• 87378-05-0 3-Benzyl-1-methoxy-2,5-dimethylpyrrol 
• 87378-06-1 1-Methoxy-2-methyl-5-(2-phenylethyl)-pyrrol 
• 87377-99-9 3-Benzyl-2,5-hexandion-bis 

Relevant academic research and scientific papers

Reactions of α-Lithio O-Alkyloximes with Diiodomethane - a Synthesis of α-Iodomethylene Oxime Ethers

Regiocontrolled deprotonation (e. g. lithiation) of acetone O-methyloxime (1), 5,6-dihydro-3-methyl-4H-1,2-oxazine (9a) and 4,5-dihydro-3-methylisoxazole (9b) is achieved within 1 minute at -65 deg C in hexane/THF.The lithiated compounds react very fast at low temperature (-65 deg C) with diiodomethane to give mainly the corresponding α-iodomethylene oxime ethers 6 and 11a, b.A radical mechanism of this reaction is dicussed.