87378-83-4Relevant academic research and scientific papers
Synthesis and antimicrobial activity of some new substituted quinoxalines
El-Atawy, Mohamed A.,Hamed, Ezzat A.,Alhadi, Mahjoba,Omar, Alaa Z.
, (2019)
A number of new symmetrically and asymmetrically 2,3-disubstituted quinoxalines were synthesized through functionalization of 2,3-dichloroquinoxaline (2,3-DCQ) with a variety of sulfur and/or nitrogen nucleophiles. The structures of the obtained compounds were established based on their spectral data and elemental analysis. The antimicrobial activity for the prepared compounds was investigated against four bacterial species and two fungal strains. The symmetrically disubstituted quinoxalines 2, 3, 4, and 5 displayed the most significant antibacterial activity, while compounds 6a, 6b, and the pentacyclic compound 10 showed considerable antifungal activity. Furthermore, compounds 3f, 6b showed broad antimicrobial spectrum against most of the tested strains.
Some Sulfur-containing Quinoxalines (1)
Campaigne, E.,McLaughlin, Astley R.
, p. 623 - 628 (2007/10/02)
A series of quinoxalines having oxygen, chlorine or sulfur substituted at the 2-position and long-chain alkyl, alkylthio, arylthio, alkylthioalkyl or arylthioalkyl groups at the 3-position have been synthesized.
