87379-51-9

Basic information

• Product Name: Methanone, (2,4-diphenyl-5-pyrimidinyl)phenyl-
• CAS NO: 87379-51-9
• Molecular Formula: C23H16N2O
• Molecular Weight: 336.393
• Mol File: 87379-51-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methanone, (2,4-diphenyl-5-pyrimidinyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2,4-diphenyl-5-pyrimidinyl)phenyl-(87379-51-9)
• EPA Substance Registry System: Methanone, (2,4-diphenyl-5-pyrimidinyl)phenyl-(87379-51-9)

Safety Data

• Hazardous Substances Data: 87379-51-9(Hazardous Substances Data)

Upstream product

• 1846-29-3 1,3-diphenyl-2-methylpropane-1,3-dione 
• 1670-14-0 benzamidine monohydrochloride 
• 85302-05-2 2-((dimethylamino)methylene)-1,3-diphenylpropane-1,3-dione 
• 618-39-3 benzamidin 

Downstream Products

• 389827-19-4 (2,4-diphenyl-pyrimidin-5-yl)-phenyl-methanol 

Relevant articles and documents

Iron Catalysis for Modular Pyrimidine Synthesis through β-Ammoniation/Cyclization of Saturated Carbonyl Compounds with Amidines

An efficient method for the modular synthesis of various pyrimidine derivatives by means of the reactions of ketones, aldehydes, or esters with amidines in the presence of an in situ prepared recyclable iron(II)-complex was developed. This operationally simple reaction proceeded with broad functional group tolerance in a regioselective manner via a remarkable unactivated β-C-H bond functionalization. Control experiments were performed to gain deep understanding of the mechanism, and the reactions are likely to proceed through a designed TEMPO complexation/enamine addition/transient α-occupation/β-TEMPO elimination/cyclization sequence.