873872-83-4Relevant academic research and scientific papers
DESYMMETRISATION PROCESS FOR THE PRODUCTION OF CYCLIC PHOSPHINES USED AS LIGANDS IN ENANTIOSELECTIVE SYNTHESIS CATALYSTS
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Page/Page column 42-43, (2010/11/27)
The present invention relates to a process for producing P-chiral cyclic phosphines, to a process for producing P-prochiral phosphine derivatives, to a process for preparing the (E,E) geometric isomers of P-chiral phosphine derivatives, to the P-prochiral phosphine derivatives, to the P-chiral cyclic phosphine derivatives, to hydroxyalkylphenylphosphine derivatives, to catalysts comprising the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, to catalysts comprising a metal and a ligand where the ligand is, is derivable from or is obtainable from the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, to the use as a catalyst of the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, to the use as a catalyst of a compound comprising a metal and a ligand where the ligand is, is derivable from or is obtainable from the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, and to a process for synthesising an organic compound whereby the synthesis includes and enantioselective reaction catalysed by the above catalyst.
Diastereoselective ring-closing metathesis: Synthesis of P-stereogenic phosphinates from prochiral phosphinic acid derivatives
Dunne, Katherine S.,Bisaro, Fabrice,Odell, Barbara,Paris, Jean-Marc,Gouverneur, Veronique
, p. 10803 - 10809 (2007/10/03)
The preparation of phosphorus-containing trienes featuring two diastereotopic vinyl moieties followed by a diastereoselective ring-closing metathesis is described. This methodology allowed for the synthesis of novel highly functionalized P-stereogenic het
