873872-95-8

Upstream product

• 61130-87-8 C₆H₁₀ClOP 
• 6052-63-7 2-phenylbut-3-en-1-ol 
• 61130-84-5 di-((E)-propen-1-yl)phosphinic acid ethyl ester 
• 873872-81-2 di-((E)-propen-1-yl)phosphinic acid 
• 873872-82-3 di(propen-1-yl)phosphinic acid ethyl ester 

Relevant academic research and scientific papers

DESYMMETRISATION PROCESS FOR THE PRODUCTION OF CYCLIC PHOSPHINES USED AS LIGANDS IN ENANTIOSELECTIVE SYNTHESIS CATALYSTS

The present invention relates to a process for producing P-chiral cyclic phosphines, to a process for producing P-prochiral phosphine derivatives, to a process for preparing the (E,E) geometric isomers of P-chiral phosphine derivatives, to the P-prochiral phosphine derivatives, to the P-chiral cyclic phosphine derivatives, to hydroxyalkylphenylphosphine derivatives, to catalysts comprising the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, to catalysts comprising a metal and a ligand where the ligand is, is derivable from or is obtainable from the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, to the use as a catalyst of the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, to the use as a catalyst of a compound comprising a metal and a ligand where the ligand is, is derivable from or is obtainable from the P-chiral cyclic phosphine derivatives or the hydroxyalkylphenylphosphine derivatives, and to a process for synthesising an organic compound whereby the synthesis includes and enantioselective reaction catalysed by the above catalyst.

Diastereoselective ring-closing metathesis: Synthesis of P-stereogenic phosphinates from prochiral phosphinic acid derivatives

The preparation of phosphorus-containing trienes featuring two diastereotopic vinyl moieties followed by a diastereoselective ring-closing metathesis is described. This methodology allowed for the synthesis of novel highly functionalized P-stereogenic het