87388-07-6Relevant academic research and scientific papers
Tandem Michael addition/isocyanide insertion into the C-C bond: A novel access to 2-acylpyrroles and medium-ring fused pyrroles
Zhang, Lingjuan,Xu, Xianxiu,Shao, Qiu-Rong,Pan, Ling,Liu, Qun
, p. 7393 - 7399 (2013/10/22)
A new reaction model, tandem Michael addition/formal isocyanide insertion into the acyl C-C bond, has been developed. Thus, a series of 2-acylpyrroles and seven-/eight-membered ring fused pyrroles were synthesized from the reaction of methyl isocyanides with enones in a single operation.
NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
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Page/Page column 27-28, (2008/12/06)
The present invention relates to novel compounds having a xanthine oxidase inhibitory effect and an uricosuric effect and pharmaceutical compositions comprising the same as an active ingredient. That is, the present invention relates nitrogen-containing heterocyclic compounds represented by the following general formula (I): wherein Y1 represents N or C(R4) ; Y2 represents N or C(R5) ; R4 and R5 independently represent an alkyl group, a hydrogen atom etc. ; one of R1 and R2 represents an optionally substituted aryl group, an alkoxygroup or an optionally substituted heterocyclic group; the other of R1 and R2 represents a haloalkyl group, a cyanogroup, ahalogenatometc.; and R3 represents a 5-tetrazolyl group or a carboxy group, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the same as an active ingredient.
Process for the preparation of 3-phenylpyrrole derivatives
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, (2008/06/13)
3-Phenylpyrrole derivatives of formula I STR1 wherein X is cyano, --CO--R3, --CO--OR3 or STR2 R1 and R2 are each independently of the other hydrogen, C1 -C6 alkyl, C1 -C6/s
