873922-26-0

Upstream product

• 452-74-4 4-bromo-3-fluorotoluene 
• 874804-12-3 5-bromo-4-fluoro-2-methylbenzenesulfonyl chloride 
• 929621-35-2 5-bromo-4-fluoro-2-methyl-1-acetylthiobenzene 
• 224185-19-7 3-bromo-4-fluoro-6-methylnitrobenzene 
• 627871-16-3 5-bromo-4-fluoro-2-methylaniline 

Downstream Products

• 248270-00-0 {2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulphanyl]phenyl}boronic acid 
• 873922-27-1 (5-bromo-4-fluoro-2-methyl-phenylsulfanyl)-acetic acid 

Relevant academic research and scientific papers

BIPHENYL SULFIDE COMPOUNDS AND INSECTICIDES AND MITICIDES

Compounds exerting high activities against various destructive insects and/or mites in agricultural and horticultural field, particularly excellent miticidal activity against Panonychus citri which is a weighty pest to citrus fruits, namely, biphenyl sulf

Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase

A novel class of HCV NS5B RNA dependent RNA polymerase inhibitors containing 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H- pyrano[3,4-b]benzofuran scaffolds were designed and synthesized. Optimization of the alkyl substituent in the pyran ring showed preference for an n-propyl group, while 5,8-disubstitution pattern is preferred for the aromatic region. Analog 19 displayed potent activity with an IC50 of 50 nM against HCV NS5B enzyme and was selective over a panel of polymerases.