87394-59-0 Usage
Chemical class
Piperazine derivatives
Structural features
Presence of a bromine atom on the 3-position of a pyridine ring and a methyl group on the piperazine ring
Potential applications
Medicinal chemistry and drug discovery
Interaction with biological targets
Ability to interact with receptors and enzymes
Value in pharmaceutical synthesis
Valuable building block for synthesizing novel pharmaceutical compounds with diverse biological activities
Research and development
Interesting molecule for further research and development in the field of medicinal chemistry
Chemical properties
Influenced by the presence of bromine and methyl groups, which can affect reactivity, solubility, and other properties
Biological effects
Depend on the specific interactions with biological targets, which can vary based on the compound's structural features and chemical properties
Check Digit Verification of cas no
The CAS Registry Mumber 87394-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,3,9 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87394-59:
(7*8)+(6*7)+(5*3)+(4*9)+(3*4)+(2*5)+(1*9)=180
180 % 10 = 0
So 87394-59-0 is a valid CAS Registry Number.
87394-59-0Relevant academic research and scientific papers
Direct uncatalyzed amination of 2-chloropyridine using a flow reactor
Hamper, Bruce C.,Tesfu, Eden
, p. 2257 - 2261 (2008/02/10)
Chloropyridines are efficiently converted into 2-amino-pyridines by uncatalyzed nucleophilic aromatic substitution (SNAr) in NMP using a continuous-flow reactor. A variety of secondary amines undergo SNAr with both electron-rich and electron-deficient 2-chloropyridines to afford 2-aminopyridines in good to excellent yield. The flow reactor, which provides a short reaction time and high temperatures up to 300°C, can overcome the activation barrier for reactions with unactivated substrates. Short reaction times result in fewer side products and can afford milligram to multigram quantities of product using continuous flow. Georg Thieme Verlag Stuttgart.
Pyridinylpiperazines, a new class of selective α2-adrenoceptor antagonists
Saari, Walfred S.,Halczenko, Wasyl,King, Stella W.,Huff, Joel R.,Guare, James P.,et al.
, p. 1696 - 1701 (2007/10/02)
A series of 1-(2-pyridinyl)piperazine derivatives was synthesized and evaluated for adrenergic activity. In vitro activity was assessed through the antagonism of clonidine's effect in the rat, isolated, field-stimulated vas deferens and by the displacemen
