87394-64-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Piperazin-1-ylnicotinamide is used as a building block for the synthesis of various drugs and active pharmaceutical ingredients due to its versatile applications in medicinal chemistry and drug discovery.
Used in Antipsychotic Agents:
PIPERAMIDE is used as an antipsychotic agent for its potential role in the development of medications that treat mental disorders, such as schizophrenia and bipolar disorder, by targeting specific receptors in the brain.
Used in Antihistaminic Agents:
2-Piperazin-1-ylnicotinamide is used as an antihistaminic agent, particularly for the development of medications that alleviate symptoms of allergies and other conditions by blocking the action of histamine.
Used in Antimalarial Agents:
PIPERAMIDE is used as an antimalarial agent for its potential role in the development of medications that treat malaria, a life-threatening disease caused by parasites transmitted through the bite of infected mosquitoes.
Used in Enzyme Inhibition:
2-Piperazin-1-ylnicotinamide is used as an enzyme inhibitor, demonstrating its potential to inhibit certain enzymes that may contribute to various diseases and conditions, thus offering a therapeutic approach to managing these health issues.
Used in Neuroprotective Agents:
PIPERAMIDE is used as a neuroprotective agent in preclinical studies, showing promise in the treatment of various neurological disorders by protecting neurons from damage and promoting their survival.
Check Digit Verification of cas no
The CAS Registry Mumber 87394-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,3,9 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 87394-64:
(7*8)+(6*7)+(5*3)+(4*9)+(3*4)+(2*6)+(1*4)=177
177 % 10 = 7
So 87394-64-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N4O/c11-9(15)8-2-1-3-13-10(8)14-6-4-12-5-7-14/h1-3,12H,4-7H2,(H2,11,15)
87394-64-7Relevant academic research and scientific papers
PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
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Paragraph 0415-0416, (2018/05/24)
The present invention provides compounds, compositions thereof, and methods of using the same.
Substituted indole compound and method and use thereof
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Paragraph 0327; 0328; 0434; 0436; 0437, (2018/11/03)
The invention provides a new indole compound, pharmaceutically acceptable salts and medicinal preparations thereof, and a use of the new indole compound in selective inhibition of 5-hydroxytryptamine reuptake and /or excitation of a 5-HT1A receptor. The invention also relates to medicinal compositions comprising the compounds, and a method for treating the central nervous system dysfunction of mammals, especially humans by using the medicinal compositions.
Pyridinylpiperazines, a new class of selective α2-adrenoceptor antagonists
Saari, Walfred S.,Halczenko, Wasyl,King, Stella W.,Huff, Joel R.,Guare, James P.,et al.
, p. 1696 - 1701 (2007/10/02)
A series of 1-(2-pyridinyl)piperazine derivatives was synthesized and evaluated for adrenergic activity. In vitro activity was assessed through the antagonism of clonidine's effect in the rat, isolated, field-stimulated vas deferens and by the displacemen