873988-08-0Relevant academic research and scientific papers
Synthetic Photoswitchable Neurotransmitters Based on Bridged Azobenzenes
Cabré, Gisela,Garrido-Charles, Aida,González-Lafont, àngels,Moormann, Widukind,Langbehn, Daniel,Egea, David,Lluch, José M.,Herges, Rainer,Alibés, Ramon,Busqué, Félix,Gorostiza, Pau,Hernando, Jordi
, p. 3780 - 3784 (2019)
Photoswitchable neurotransmitters of ionotropic kainate receptors were synthesized by tethering a glutamate moiety to disubstituted C2-bridged azobenzenes, which were prepared through a novel methodology that allows access to diazocines with higher yields
Diazocine Derivatives: A Family of Azobenzenes for Photochromism with Highly Enhanced Turn-On Fluorescence
Zhu, Qian,Wang, Suning,Chen, Pangkuan
, p. 4025 - 4029 (2019)
π-Conjugated azobenzene derivatives were reported to couple azo moieties with aryl fluorophore. Using the photochemistry of the C2-bridged azobenzene, we have accomplished two diazocine-based photoswitching molecules (cAz1 and cAz2). In additio
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light
Bauer, Katharina,Berger, Benedict-Tilman,Chaikuad, Apirat,Knapp, Stefan,Koch, Pierre,Laufer, Stefan,Reynders, Martin,Trauner, Dirk
, p. 20178 - 20183 (2021)
Covalent kinase inhibitors account for some of the most successful drugs that have recently entered the clinic and many others are in preclinical development. A common strategy is to target cysteines in the vicinity of the ATP binding site using an acryla
