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Sarkomycin, also known as Aclarubicin, is an anthracycline antibiotic and antineoplastic agent derived from Streptomyces galilaeus. It functions as a topoisomerase II inhibitor, which prevents DNA replication by stabilizing the topoisomerase II-DNA complex, ultimately leading to DNA strand breaks and cell death. Sarkomycin is primarily used in the treatment of various types of cancer, including leukemia, lymphoma, and other malignancies. Its mechanism of action involves intercalating into DNA, which disrupts the DNA helix and inhibits RNA and DNA synthesis, thereby inhibiting cell proliferation. Due to its potential cardiotoxicity, sarkomycin is administered with caution, and its use is often limited to patients who cannot tolerate other anthracycline drugs.

874-21-5

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874-21-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 874-21-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,7 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 874-21:
(5*8)+(4*7)+(3*4)+(2*2)+(1*1)=85
85 % 10 = 5
So 874-21-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H8O3/c1-4-5(7(9)10)2-3-6(4)8/h5H,1-3H2,(H,9,10)/t5-/m1/s1

874-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Cyclopentanecarboxylicacid, 2-methylene-3-oxo-, sodium salt (1:1)

1.2 Other means of identification

Product number -
Other names 2-Methylene-3-oxocyclopentanecarboxylic acid sodium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:874-21-5 SDS

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